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Serpin H1

Brief Information

Name:Serpin H1
Target Synonym:47 kDa heat shock protein,Arsenic-transactivated protein 3,AsTP3,Cell proliferation-inducing gene 14 protein,Rheumatoid arthritis-related antigen RA-A47,HSP47
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
SE1-H5224 Human Human Serpin H1 Protein, His Tag
SE1-H5224-structure
SE1-H5224-sds
ACRO Quality

Synonym Name

SERPINH1,Serpin H1,HSP47,CBP1,CBP2,SERPINH2,PIG14,AsTP3,Colligin,OI10,PPROM,RA-A47,gp46

Background

Serpin H1 is also known as SERPINH1, 47 kDa heat shock protein (HSP47), Collagen-binding protein (Colligin), Arsenic-transactivated protein 3 (AsTP3), which belongs to the serpin family. SERPINH1 binds specifically to collagen. SERPINH1 / HSP47 could be involved as a chaperone in the biosynthetic pathway of collagen.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
BMS-986263 BMS-986263; ND-L02-s0201 Phase 2 Clinical Hokkaido University, Sapporo Medical University, Nitto Denko Metabolic Dysfunction-Associated Steatotic Liver Disease; Idiopathic Pulmonary Fibrosis; Liver Cirrhosis; Fibrosis; Hepatic Insufficiency Details
BMS-986263 BMS-986263; ND-L02-s0201 Phase 2 Clinical Hokkaido University, Sapporo Medical University, Nitto Denko Metabolic Dysfunction-Associated Steatotic Liver Disease; Idiopathic Pulmonary Fibrosis; Liver Cirrhosis; Fibrosis; Hepatic Insufficiency Details

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